منابع مشابه
Obesity--is it a genetic disorder?
Obesity is one of the most pressing problems in the industrialized world. Twin, adoption and family studies have shown that genetic factors play a significant role in the pathogenesis of obesity. Rare mutations in humans and model organisms have provided insights into the pathways involved in body weight regulation. Studies of candidate genes indicate that some of the genes involved in pathways...
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Dear Editor An important problem to manage diabetes mellitus is controlling the patients` blood glucose. Fluctuation of blood glucose results in molecular biochemistry change and can result in unwanted diabetic complications (1). In clinical practice, hemoglobin A1C (HbA1C) is a common useful laboratory test to follow-up patients with diabetes (2). Sometimes, an unexpecte...
متن کاملIt Is Just Attention-Deficit Hyperactivity Disorder…or Is It?
CASE Carly is a 5-year-old girl who presents for an interdisciplinary evaluation due to behaviors at school and home suggestive of attention-deficit hyperactivity disorder (ADHD). Parent report of preschool teacher concerns was consistent with ADHD. Psychological testing showed verbal, visual-spatial, and fluid reasoning IQ scores in the average range; processing speed and working memory were b...
متن کاملCommon Genetic Variant of insig2 Gene rs7566605 Polymorphism Is Associated with Severe Obesity in North India
Background: Obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases. The aim of this study was to examine the association of INSIG2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in North Indian subjects. Methods: The variants were investig...
متن کاملAsthma is a complex genetic disorder
affected by a myriad of environmental stimuli, leading to suggestions that asthma is not a single disease but a syndrome of related diseases – a situation that complicates the development of relevant animal models (Busse and Lemanske, 2001; Drazen et al., 2000). Asthma is characterized by chronic airway inflammation, airway hyperresponsiveness (AHR) and reversible airflow obstruction. These thr...
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ژورنال
عنوان ژورنال: Journal of Internal Medicine
سال: 2003
ISSN: 0954-6820,1365-2796
DOI: 10.1046/j.1365-2796.2003.01242.x